Innovation has become the most important and effective constituting element in the system of success of both the individual and the institution. Innovation on all levels, is a topic that is becoming impossible to ignore or to be taken lightly. Functional analysis, agility and non-traditional problem-solving methods of thinking, are becoming more essential than ever, for the continuous evolution of the business models of organizations and institutes. Keeping-up in the contest of Innovative Entrepreneurship, is a key-success factor for any organization to maintain and develop its market position, adapt to the rapidly changing market factors, sustain its market share within competing environments, as well as continuously improve its value-proposition offerings to better serve their dynamic and complex market needs. Human intellect is always breaking the chains towards more forward-looking sustainable methods for bridging all the gaps, fulfilling both current and future needs, with more advanced SMART solutions and services.